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Beamline News


October 15-16, 2020: Registration is now open!

Sept. 23, 2020

Mid-IR is hosting a workshop!

When: October 15-16, 2020

Presenter: Christophe Sandt, Beamline Scientist, SOLEIL synchrotron

Topics: Theory, Preprocessing Data, Data Exploration, Imaging, Classification and Prediction

Location: webinar, information sent with registration

Who can attend: Anyone who is interested! Please register:


Having trouble with registration? Please send us an email with the subject Mid-IR workshop.


October 14, 2020 - 12:00 (CST) → 14:00 (CST) Technical Help Session

  • Provide online technical support for the installation of Quasar to workshop attendees.

October 15, 2020 - 08:00 (CST) → 10:00 (CST) First Session - Theory and Preprocessing Data

  • Theory
    • Data Collection Strategy
    • Need for Multivariate Analysis and Clustering
    • Example Applications (Bio-Spectroscopy)
    • Preprocessing Theory
  • Preprocessing Data
    • Hands on training with Quasar
    • Quality control
    • Baseline correction, normalization, derivation
    • Smoothing/denoising
    • EMSC - Extended Multiplicative Scatter Correction
    • Advanced preprocessing that exist but not demonstrated (ATR, atmospheric suppression, interference fringes, KK, KM)

October 15, 2020 - 12:00 (CST) → 14:00 (CST) Second Session - Data Exploration and Imaging

  • Data Exploration: PCA
    • Hands On
    • Theory and Interpretation
    • PCA Classification (SIMCA)
  • Imaging
    • Generate Images in Quasar
    • Manipulate Images: Graphical and "Intelligent" selection of Data

October 16, 2020 - 08:00 (CST) → 10:00 (CST) Third Session - Classification and Prediction

  • Classification and Prediction
    • Unsupervised Clustering (K-Means, HCA)
    • Supervised Clustering (KNN, CART, RFC, ANN, logit)
    • Theory: Calibration and Validation
    • Test and Score
    • Prediction

Christophe Sandt - Biography

Christophe Sandt was trained as a biochemist and is currently beamline scientist at the SOLEIL synchrotron near Paris, France. He earned a PhD in Biospectroscopy from the Pharmacy University of Reims Champagne-Ardenne under the guidance of Prof. Manfait and Sockalingum. He has a 20 year long experience in the field of vibrational microspectroscopy of biological materials, cells and tissues including two post-doctoral fellowships in Canada, at the Chemistry Department of Université de Montréal working with Prof. Lafleur, and at the Chemistry Department of St Francis Xavier University with Prof. Pink and Smith-Palmer. His first research interests focused on the early identification of pathogenic microorganisms by infrared spectroscopy, the study of biocide penetration in bacterial biofilms with ATR-FTIR, and pioneering the analysis of bacterial biofilms by Raman microspectroscopy. He joined the French national synchrotron light source, SOLEIL, in 2008 and has since been helping scientists perform experiment in various fields of science such as cultural heritage, plant biology, cell chemistry, catalysis, astrophysics... He has used the bright IR synchrotron light to conduct various studies in biochemistry: to profile induced pluripotent and embryonic stem cells, to monitor tyrosine kinase activity in multiresistant hematopietic progenitor cells, to study the chemical changes associated with tumor hypoxia, to follow the penetration of IR probes in living cells and tissues, to study abnormal protein conformation in diverse neurodegenerative diseases.